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Pitstop 1
CAS No. 1332879-51-2
Pitstop 1 ( Pitstop-1;Pitstop1 )
Catalog No. M11323 CAS No. 1332879-51-2
A potent, selective inhibitor of clathrin-independent endocytosis with IC50 of 18 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NamePitstop 1
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective inhibitor of clathrin-independent endocytosis with IC50 of 18 uM.
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DescriptionA potent, selective inhibitor of clathrin-independent endocytosis with IC50 of 18 uM (inhibition of clathrin TD-amphiphysin B/C complex formation); inhibits endocytic recycling of synaptic vesicles in neurons and in situ.
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SynonymsPitstop-1;Pitstop1
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PathwayOthers
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TargetClathrin
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RecptorClathrin
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Research Area——
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Indication——
Chemical Information
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CAS Number1332879-51-2
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Formula Weight404.37
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Molecular FormulaC19H13N2NaO5S
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Purity>98% (HPLC)
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Solubility——
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SMILESNC1=CC=C(CN2C(C3=CC(S(=O)(O[Na])=O)=CC4=C3C(C2=O)=CC=C4)=O)C=C1
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Chemical Name2-(4-Aminobenzyl)-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-5-sulfonic acid sodium salt
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. von Kleist L, et al. Cell. 2011 Aug 5;146(3):471-84.
2. Nilewski LG, et al. ACS Chem Neurosci. 2017 Aug 14. doi: 10.1021/acschemneuro.7b00138.
2. Nilewski LG, et al. ACS Chem Neurosci. 2017 Aug 14. doi: 10.1021/acschemneuro.7b00138.
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