Cart
sales@molnova.com
Pitstop 1
CAS No. 1332879-51-2
Pitstop 1( Pitstop-1 | Pitstop1 )
Catalog No. M11323 CAS No. 1332879-51-2
A potent, selective inhibitor of clathrin-independent endocytosis with IC50 of 18 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NamePitstop 1
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent, selective inhibitor of clathrin-independent endocytosis with IC50 of 18 uM.
-
DescriptionA potent, selective inhibitor of clathrin-independent endocytosis with IC50 of 18 uM (inhibition of clathrin TD-amphiphysin B/C complex formation); inhibits endocytic recycling of synaptic vesicles in neurons and in situ.
-
In Vitro——
-
In Vivo——
-
SynonymsPitstop-1 | Pitstop1
-
PathwayOthers
-
TargetClathrin
-
RecptorClathrin
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1332879-51-2
-
Formula Weight404.37
-
Molecular FormulaC19H13N2NaO5S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESNC1=CC=C(CN2C(C3=CC(S(=O)(O[Na])=O)=CC4=C3C(C2=O)=CC=C4)=O)C=C1
-
Chemical Name2-(4-Aminobenzyl)-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-5-sulfonic acid sodium salt
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. von Kleist L, et al. Cell. 2011 Aug 5;146(3):471-84.
2. Nilewski LG, et al. ACS Chem Neurosci. 2017 Aug 14. doi: 10.1021/acschemneuro.7b00138.
molnova catalog
related products
-
Pitstop 1
A potent, selective inhibitor of clathrin-independent endocytosis with IC50 of 18 uM.
-
Pitstop 2 (b)
A small molecule inhibitor of clathrin terminal domain and inhibits clathrin-mediated endocytosis.
-
AK306
AK306 is a small molecule clathrin heavy chain (CLTC/CHC) binding compound that induces arrest and apoptosis of the HCT116 colon cancer cell line with EC50 of 50 nM.
